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HMGBiotech 高迁移率蛋白、质粒、抗体-相关技术文章

更新时间:2024-07-20&苍产蝉辫;&苍产蝉辫;&苍产蝉辫;&苍产蝉辫;&苍产蝉辫;&苍产蝉辫;浏览次数:285

HMGBiotech  高迁移率蛋白、质粒、抗体

 

HMGBiotech公司介绍

HMGBiotech公司研发的HMGB 1是细胞核的一个组成部分,在基因组的组织和表达中具有多种功能。HMG生物技术SRL为活跃在这一领域的其他研究人员和公司提供试剂、服务和想法。它还有助于比安奇实验室开发分析和试剂。

HMGBiotech是一家生物技术公司,由HMGB领域的 ling xian 科学家Marco E. Bianchi创立。

HMGBiotech是唯测颈一家生产HMGB1质量控制氧化还原变体的生产商。 该公司为活跃于这一有前途领域的其他研究人员和公司提供试剂、服务和想法,并帮助 Bianchi 实验室开发检测方法和试剂。

HMGB1是细胞核的一个组成部分,在基因组的组织和表达中具有多种功能。当细胞因损伤(病毒、机械或化学创伤、中毒)而死亡时,HMGB1 被释放并被附近细胞中的受体吸收。此外,处于严重压力下的细胞甚至在死亡前就会分泌HMGB1。存活的细胞会发出一线反应 - 炎症 - 并试图替换死细胞并重建受损组织。HMGB1 促进恢复和再生,例如梗死后心脏的恢复和再生。然而,过多的 HMGB1 与脓毒症(过度炎症导致急性痛苦并最终死亡)、关节炎、动脉粥样硬化和癌症转移有关。

anti HMGB1单克隆抗体

小鼠单克隆 IgG1 DPH1.1 是通过向 C57BL/6 小鼠注射 17 聚体肽 P1 KGKPDAAKKGVVKAEKS) 产生的。杂交瘤通过标准技术从脾细胞中产生,并通过 ELISA 针对免疫原和全长 HMGB1 进行测试。

DPH1.1 mAb 可识别所有哺乳动物 HMGB1,包括人、小鼠和大鼠。无法识别 HMGB2

DPH1.1 mAb 可用于蛋白质印迹 (WB)。

DPH1.1 mAb 在跨孔迁移试验中阻断 HMGB1 诱导的细胞迁移。

在体内,静脉内施用 DPH1.1 mAb 220 μg/小鼠) 可阻断炎症细胞募集到坏死和感染部位。

本产物仅供研究使用,不能用于人体。

 

HMGBiotech公司热销产物

产物名称

货号

规格

100 ug Fully reduced HMGB1, LPS free

HM-115

100 ug

50 ug Fully reduced HMGB1, LPS free

HM-116

50 ug

100 ug Disulfide HMGB1, LPS free

HM-121

100 ug

100 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-012

100 ug

50 ug Disulfide HMGB1, LPS free

HM-122

50 ug

500 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-013

500 ug

1 mg HMGB1 for biochemistry

HM-100

1 mg

2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay

HM-014

2.5 mg

250 ug HMGB1 biochemistry

HM-101

250 ug

25 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-011

25 ug

15 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-053

15 ug

15 ug Fully reduced HMGB1, LPS free

HM-117

15 ug

10 ug Disulfide HMGB1, LPS free

HM-123

10 ug

15 ug Non-oxidizable HMGB1, LPS free

HM-133

15 ug

250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in   migration

HM-170

250 ug

100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in   migration

HM-171

100 ug

50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in   migration

HM-172

50 ug

15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in   migration

HM-173

15 ug

50 ug HMGB1 15N labelled for Mass Spectrometry

HM-180

50 ug

5 ug HMGB1 15N labelled for Mass Spectrometry

HM-181

5 ug

2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-190

2.5 mg

500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-191

500 ug

100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-192

100 ug

25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-193

25 ug

Control cell lysates from Hmgb1 +/+

HM-001

请咨询

Control cell lysates from Hmgb1 -/-

HM-002

请咨询

1 mg BoxB from HMGB1, LPS-free and tested in migration assay

HM-050

1 mg

250 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-051

250 ug

100 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-052

100 ug

500 ug Fully reduced HMGB1, LPS free

HM-114

500 ug

250 ug Disulfide HMGB1, LPS free

HM-120

250 ug

500 ug Non-oxidizable HMGB1, LPS free

HM-130

500 ug

100 ug Non-oxidizable HMGB1, LPS free

HM-131

100 ug

50 ug Non-oxidizable HMGB1, LPS free

HM-132

50 ug

500 ug HMGB2, LPS-free and tested in migration assay

HM-151

500 ug

100 ug HMGB2, LPS-free and tested in migration assay

HM-152

100 ug

50 ug HMGB2, LPS-free and tested in migration assay

HM-153

50 ug

Embryonic fibroblasts immortalized with large T antigen. One vial of   -/- cells and one vial of +/+ cells

HM-201

2

Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/-   cells and one vial of +/+ cells

HM-221

2

Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the   3T3 method. One vial of cells, and

HM-223

2

HMGB1 Isoforms Kit - Test size

HM-030

请咨询

Embryonic fibroblasts immortalized with the 3T3 method. One vial of   Hmgb2-/- cells and one vial of +/+ cells

HM-251

2

HMGB1 Isoforms Kit - Regular size

HM-031

请咨询

20 ug p-mHMG1

HM-300

20 ug

50 ug Terminally oxidized HMGB1, LPS free

HM-062

50 ug

20 ug p-mHMG1tag

HM-301

20 ug

100 ug Terminally oxidized HMGB1, LPS free

HM-061

100 ug

20 ug pEGFP-HMGB1

HM-302

20 ug

250 ug Terminally oxidized HMGB1, LPS free

HM-060

250 ug

20 ug pcDNA/FL-RAGE plasmid

HM-310

20 ug

 


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